Chromatin-state discovery and genome annotation with ChromHMM.

Abstract

Noncoding DNA regions have central roles in human biology, evolution, and disease. ChromHMM helps to annotate the noncoding genome using epigenomic information across one or multiple cell types. It combines multiple genome-wide epigenomic maps, and uses combinatorial and spatial mark patterns to infer a complete annotation for each cell type. ChromHMM… (More)
DOI: 10.1038/nprot.2017.124

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