Chromatin remodeling in somatic cells injected into mature pig oocytes.

@article{Bui2006ChromatinRI,
  title={Chromatin remodeling in somatic cells injected into mature pig oocytes.},
  author={H A Bui and Nguyen Van Thuan and Teruhiko Wakayama and Takashi Miyano},
  journal={Reproduction},
  year={2006},
  volume={131 6},
  pages={1037-49}
}
We examined the involvement of histone H3 modifications in the chromosome condensation and decondensation of somatic cell nuclei injected into mature pig oocytes. Nuclei of pig granulosa cells were transferred into in vitro matured intact pig oocytes, and histone H3 phosphorylation, acetylation, and methylation were examined by immunostaining with specific antibodies in relation to changes in chromosome morphology. In the condensed chromosomes of pig oocytes at metaphase II, histone H3 was… CONTINUE READING

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