Chromatin regulatory mechanisms in pluripotency.

@article{Lessard2010ChromatinRM,
  title={Chromatin regulatory mechanisms in pluripotency.},
  author={Julie A Lessard and Gerald R Crabtree},
  journal={Annual review of cell and developmental biology},
  year={2010},
  volume={26},
  pages={503-32}
}
Stem cells of all types are characterized by a stable, heritable state permissive of multiple developmental pathways. The past five years have seen remarkable advances in understanding these heritable states and the ways that they are initiated or terminated. Transcription factors that bind directly to DNA and have sufficiency roles have been most easy to investigate and, perhaps for this reason, are most solidly implicated in pluripotency. In addition, large complexes of ATP-dependent… CONTINUE READING

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