Chromatin regulates origin activity in Drosophila follicle cells

@article{Aggarwal2004ChromatinRO,
  title={Chromatin regulates origin activity in Drosophila follicle cells},
  author={Bhagwan Das Aggarwal and Brian R Calvi},
  journal={Nature},
  year={2004},
  volume={430},
  pages={372-376}
}
It is widely believed that DNA replication in multicellular animals (metazoa) begins at specific origins to which a pre-replicative complex (pre-RC) binds. Nevertheless, a consensus sequence for origins has yet to be identified in metazoa. Origin identity can change during development, suggesting that there are epigenetic influences. A notable example of developmental specificity occurs in Drosophila, where somatic follicle cells of the ovary transition from genomic replication to exclusive re… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 141 extracted citations

Defining the replication program through the chromatin landscape.

Critical reviews in biochemistry and molecular biology • 2011
View 5 Excerpts
Highly Influenced

On the histone acetyltransferase hMOF

View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Similar Papers

Loading similar papers…