Chromatin reassembly signals the end of DNA repair.

  title={Chromatin reassembly signals the end of DNA repair.},
  author={Chin-chuan Chen and Jessica E Tyler},
  journal={Cell cycle},
  volume={7 24},
The packaging of the eukaryotic genome into chromatin provides a formidable obstacle to the machinery that mediates genomic processes such as transcription, repair and replication. The cell solves this accessibility problem during double-strand DNA repair by removing the histone proteins flanking the DNA lesion. Presumably then, the repaired DNA is subsequently reassembled into chromatin in order to allow the epigenetic information to be restored and to repackage and protect the genome. Our… CONTINUE READING