Chromatin insulators: linking genome organization to cellular function.

@article{PhillipsCremins2013ChromatinIL,
  title={Chromatin insulators: linking genome organization to cellular function.},
  author={Jennifer E Phillips-Cremins and Victor G Corces},
  journal={Molecular cell},
  year={2013},
  volume={50 4},
  pages={461-74}
}
A growing body of evidence suggests that insulators have a primary role in orchestrating the topological arrangement of higher-order chromatin architecture. Insulator-mediated long-range interactions can influence the epigenetic status of the genome and, in certain contexts, may have important effects on gene expression. Here we discuss higher-order… CONTINUE READING