Chromatin immunoprecipitation in microfluidic droplets: towards fast and cheap analyses.

@article{Teste2017ChromatinII,
  title={Chromatin immunoprecipitation in microfluidic droplets: towards fast and cheap analyses.},
  author={Bruno Teste and J{\'e}r{\^o}me Champ and Arturo Londo{\~n}o-Vallejo and St{\'e}phanie Descroix and Laurent Malaquin and J. L. Viovy and Irena Dra{\vs}kovi{\vc} and Guillaume Mottet},
  journal={Lab on a chip},
  year={2017},
  volume={17 3},
  pages={
          530-537
        }
}
Genetic organization is governed by the interaction of DNA with histone proteins, and differential modifications of these proteins is a fundamental mechanism of gene regulation. Histone modifications are primarily studied through chromatin immunoprecipitation (ChIP) assays, however conventional ChIP procedures are time consuming, laborious and require a large number of cells. Here we report for the first time the development of ChIP in droplets based on a microfluidic platform combining… 
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