Chromatin boundaries: Punctuating the genome

  title={Chromatin boundaries: Punctuating the genome},
  author={R E Kellum and S Elgin},
  journal={Current Biology},
Transcriptional enhancers are constrained to act within domains defined by boundary elements. How these elements work is a mystery. A recent study emphasizes their autonomous activity; another emphasizes their dependence on nuclear organization. Both effects need to be accounted for by any successful model. 

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