Chromatin as dynamic 10-nm fibers

@inproceedings{Maeshima2014ChromatinAD,
  title={Chromatin as dynamic 10-nm fibers},
  author={Kazuhiro Maeshima and Ryosuke Imai and Sachiko Tamura and Tadasu Nozaki},
  booktitle={Chromosoma},
  year={2014}
}
Since Flemming described a nuclear substance in the nineteenth century and named it “chromatin,” this substance has fascinated biologists. What is the structure of chromatin? DNA is wrapped around core histones, forming a nucleosome fiber (10-nm fiber). This fiber has long been assumed to fold into a 30-nm chromatin fiber and subsequently into helically folded larger fibers or radial loops. However, several recent studies, including our cryo-EM and X-ray scattering analyses, demonstrated that… CONTINUE READING

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