Chromatin and RNAi factors protect the C. elegans germline against repetitive sequences.

@article{Robert2005ChromatinAR,
  title={Chromatin and RNAi factors protect the C. elegans germline against repetitive sequences.},
  author={Val{\'e}rie J.P. Robert and Titia Sijen and Josien C. van Wolfswinkel and Ronald H. A. Plasterk},
  journal={Genes & development},
  year={2005},
  volume={19 7},
  pages={782-7}
}
Protection of genomes against invasion by repetitive sequences, such as transposons, viruses, and repetitive transgenes, involves strong and selective silencing of these sequences. During silencing of repetitive transgenes, a trans effect ("cosuppression") occurs that results in silencing of cognate endogenous genes. Here we report RNA interference (RNAi) screens performed to catalog genes required for cosuppression in the Caenorhabditis elegans germline. We find factors with a putative role in… CONTINUE READING
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References

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Showing 1-10 of 48 references

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