Chromatin Organization by Repetitive Elements (CORE): A Genomic Principle for the Higher-Order Structure of Chromosomes

@inproceedings{Tang2011ChromatinOB,
  title={Chromatin Organization by Repetitive Elements (CORE): A Genomic Principle for the Higher-Order Structure of Chromosomes},
  author={Shao-Jun Tang},
  booktitle={Genes},
  year={2011}
}
Eukaryotic genomes contain a large amount of DNA repeats (also known as repetitive DNA, repetitive elements, and repetitive sequences). Here, I propose a role of repetitive DNA in the formation of higher-order structures of chromosomes. The central idea of this theory is that chromatin regions with repetitive sequences pair with regions harboring homologous repeats and that such somatic repeat pairing (RP) assembles repetitive DNA chromatin into compact chromosomal domains that specify… CONTINUE READING

Citations

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Potential Role of Phase Separation of Repetitive DNA in Chromosomal Organization

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New Evidence for the Theory of Chromosome Organization by Repetitive Elements (CORE)

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