Chromatin: a tunable spring at work inside chromosomes.

  title={Chromatin: a tunable spring at work inside chromosomes.},
  author={Eli Ben-Ha{\"i}m and Annick Lesne and J M Victor},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  volume={64 5 Pt 1},
This paper focuses on mechanical aspects of chromatin biological functioning. Within a basic geometric modeling of the chromatin assembly, we give a complete set of elastic constants (twist and bend persistence lengths, stretch modulus and twist-stretch coupling constant) of the so-called 30-nm chromatin fiber, in terms of DNA elastic properties and geometric properties of the fiber assembly. The computation naturally embeds the fiber within a current analytical model known as the "extensible… CONTINUE READING