Chromatic pupillometry dissects function of the three different light-sensitive retinal cell populations in RPE65 deficiency.

@article{Lorenz2012ChromaticPD,
  title={Chromatic pupillometry dissects function of the three different light-sensitive retinal cell populations in RPE65 deficiency.},
  author={Birgit Lorenz and Elisabeth Strohmayr and Steffen Zahn and C Friedburg and Martin Kramer and M N Preising and Knut Stieger},
  journal={Investigative ophthalmology & visual science},
  year={2012},
  volume={53 9},
  pages={5641-52}
}
PURPOSE The aim of the study was to objectively characterize the function of rods, cones, and intrinsic photosensitive retinal ganglion cells (ipRGCs) in patients with RPE65 mutations by using two published protocols for chromatic pupillometry, and to correlate the data with the clinical phenotype. METHODS The study group comprised 11 patients with RPE65 mutations, and for control purposes, 32 healthy probands and 2 achromats. A custom-made binocular chromatic pupillometer (Bino I) connected… CONTINUE READING
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