Chromanyl-isoxazolidines as Antibacterial agents: Synthesis, Biological Evaluation, Quantitative Structure Activity Relationship, and Molecular Docking Studies.

Abstract

Regio- and stereoselective 1,3-dipolar cycloadditions of C-(chrom-4-one-3-yl)-N-phenylnitrones (N) with different mono-substituted, disubstituted, and cyclic dipolarophiles were carried out to obtain substituted N-phenyl-3'-(chrom-4-one-3-yl)-isoxazolidines (1-40). All the synthesized compounds were assayed for their in vitro antibacterial activity and… (More)
DOI: 10.1111/cbdd.12653

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@article{Singh2016ChromanylisoxazolidinesAA, title={Chromanyl-isoxazolidines as Antibacterial agents: Synthesis, Biological Evaluation, Quantitative Structure Activity Relationship, and Molecular Docking Studies.}, author={Gagandeep Singh and Anuradha Sharma and Harpreet Kaur and Mohan Paul Singh Ishar}, journal={Chemical biology & drug design}, year={2016}, volume={87 2}, pages={213-23} }