Choroidal melanomas: correlation of NMR spectroscopy and MR imaging.

  title={Choroidal melanomas: correlation of NMR spectroscopy and MR imaging.},
  author={John Moshe Gomori and Robert I. Grossman and Jerry A. Shields and James Jay Augsburger and Peter Mwita Joseph and D DeSimeone},
  volume={158 2},
Six freshly enucleated, unfixed human eyes with choroidal melanomas were imaged on a 1.4-T superconducting magnetic resonance (MR) imaging system. Immediately thereafter the eyes were sectioned, and tumor samples were removed for study on a variable-field (0.19-1.4 T) nuclear MR spectroscopy unit. Shorter T1 and T2 relaxation times were observed in those tumors with the greater concentrations of melanin. This is believed to result from the paramagnetic effect of radicals known to exist in… CONTINUE READING

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