Chorionic mosaicism: association with fetal loss but not with adverse perinatal outcome.

@article{Wapner1992ChorionicMA,
  title={Chorionic mosaicism: association with fetal loss but not with adverse perinatal outcome.},
  author={Ronald J. Wapner and Joe Leigh Simpson and Mitchell S. Golbus and Julia M Zachary and David H. Ledbetter and Robert J Desnick and Sarah E. Fowler and Laird G. Jackson and Herbert A. Lubs and Robert Mahony},
  journal={Prenatal diagnosis},
  year={1992},
  volume={12 5},
  pages={347-55}
}
Cytogenetic data from the United States NICHD collaborative study of chorionic villus sampling (CVS) were used to evaluate the clinical significance of chorionic mosaicism. The 10,754 patients with normal cytogenetic results were compared with 108 patients (1.0 per cent) with placental mosaicism and 181 patients (1.6 per cent) with pseudo-mosaicism. Of the pregnancies intended to continue, the pregnancy loss rate was significantly greater in patients with placental mosaicism than in the… CONTINUE READING
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