Chorionic disk extravillous trophoblasts in placental diagnosis.

@article{Stanek2011ChorionicDE,
  title={Chorionic disk extravillous trophoblasts in placental diagnosis.},
  author={Jerzy Stanek},
  journal={American journal of clinical pathology},
  year={2011},
  volume={136 4},
  pages={
          540-7
        }
}
  • J. Stanek
  • Published 1 October 2011
  • Medicine, Biology
  • American journal of clinical pathology
To study clinical and placental associations of increased amount of chorionic disk extravillous trophoblast (IAEVT), the frequency of selected clinical and placental parameters of 189 consecutive cases with IAEVT, defined as more than 5 cell islands and/or placental septa per placental section, were compared with those for all remaining 1,006 placentas examined during the same period. IAEVT was statistically significantly associated with preeclampsia, decidual arteriolopathy, placental… 
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  • Medicine, Biology
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  • J. Stanek
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  • J. Stanek
  • Medicine
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Placental examination in nonmacerated stillbirth versus neonatal mortality
  • J. Stanek
  • Medicine
    Journal of perinatal medicine
  • 2018
TLDR
Placental examination in Neonatal mortality shows thrombotic pathology related to umbilical cord compromise and features of shallow placental implantation that are similar to those in nonmacerated stillbirth; however, the features of placental abruption were more common in recent antepartum death, as were the features related to neonatal congenital malformations in neonatal deaths.
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References

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Membrane microscopic chorionic pseudocysts are associated with increased amount of placental extravillous trophoblasts
TLDR
The increased extravillous trophoblast accumulation and secretory activity is associated with MCP formation, and the findings place MCP among other placental lesions associated with extravillus trophoblasts accumulation and possibly dysfunction.
Placental Membrane and Placental Disc Microscopic Chorionic Cysts Share Similar Clinicopathologic Associations
  • J. Stanek
  • Medicine
    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • 2011
TLDR
Both membrane and chorionic disc MCC, frequently associated with an excessive amount of extravillous trophoblastic lesions associated with chronic placental hypoxia, should be regarded as members of the family of extra Village trophoblast lesions.
Microscopic Chorionic Pseudocysts in Placental Membranes: A Histologic Lesion of in Utero Hypoxia
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  • Medicine
    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
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TLDR
Highly statistically significant associations of mccpm with preeclampsia and a cluster of placental lesions known to be linked to placental hypoxia indicate that the mCCpm form in response to Hypoxia, particularly in patients with preeClampsia; mccPM should therefore be regarded and reported as a hypoxIA-associated placental lesion.
Acute and chronic placental membrane hypoxic lesions
TLDR
Based on the above results, LN, a membrane infarction, appears to be an acute membrane hypoxic lesion, while MCP is a chronic lesion related to a more widespread extravillous trophoblasts accumulation in the placental disk.
Diagnosing placental membrane hypoxic lesions increases the sensitivity of placental examination.
  • J. Stanek
  • Medicine, Biology
    Archives of pathology & laboratory medicine
  • 2010
TLDR
Recognizing placental membrane hypoxic lesions increases the sensitivity of placental examination in diagnosing placental hypoxia by at least 15%.
Occult Placenta Accreta: The Missing Link in the Diagnosis of Abnormal Placentation
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  • Medicine
    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
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TLDR
Although asymptomatic, OPA features the same histopathology as clinical placenta accreta and may share same pathogenesis, which may include decidual deficiency, abnormal trophoblast/ decidua interaction, and/or hypoxia.
Trophoblast alterations in the placental bed in relation to physiological changes in spiral arteries
TLDR
The hypothesis is put forward that in the absence of physiological changes a disturbed stromal migration is caused by intrinsic (trophoblastic) or extrinsic (interstitial of vascular) factors expressed by the augmentation of the multinucleated cells at the decidual–myometrial junction.
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