Chorein sensitivity of cytoskeletal organization and degranulation of platelets.


Chorea-acanthocytosis (ChAc), a lethal disease caused by defective chorein, is characterized by neurodegeneration and erythrocyte acanthocytosis. The functional significance of chorein in other cell types remained ill-defined. The present study revealed chorein expression in blood platelets. As compared to platelets from healthy volunteers, platelets from… (More)
DOI: 10.1096/fj.13-229286