Chordoma Characterization of Significant Changes of the DNA Methylation Pattern

@inproceedings{Rinner2013ChordomaCO,
  title={Chordoma Characterization of Significant Changes of the DNA Methylation Pattern},
  author={Beate Rinner and Andreas Weinhaeusel and Birgit Lohberger and Elke Verena Froehlich and Walter Pulverer and Carina Fischer and Katharina Meditz and Susanne Scheipl and Slave Trajanoski and Christian Guelly and Andreas Leithner and Bernadette Liegl},
  booktitle={PloS one},
  year={2013}
}
Chordomas are rare mesenchymal tumors occurring exclusively in the midline from clivus to sacrum. Early tumor detection is extremely important as these tumors are resistant to chemotherapy and irradiation. Despite continuous research efforts surgical excision remains the main treatment option. Because of the often challenging anatomic location early detection is important to enable complete tumor resection and to reduce the high incidence of local recurrences. The aim of this study was to… CONTINUE READING