Chordin is required for neural but not axial development in sea urchin embryos.

@article{Bradham2009ChordinIR,
  title={Chordin is required for neural but not axial development in sea urchin embryos.},
  author={Cynthia A. Bradham and Catherine Oikonomou and Alexander K{\"u}hn and Amanda B. Core and Joshua Wexler Modell and D R Mcclay and Albert J. Poustka},
  journal={Developmental biology},
  year={2009},
  volume={328 2},
  pages={221-33}
}
The oral-aboral (OA) axis in the sea urchin is specified by the TGFbeta family members Nodal and BMP2/4. Nodal promotes oral specification, whereas BMP2/4, despite being expressed in the oral territory, is required for aboral specification. This study explores the role of Chordin (Chd) during sea urchin embryogenesis. Chd is a secreted BMP inhibitor that plays an important role in axial and neural specification and patterning in Drosophila and vertebrate embryos. In Lytechinus variegatus… CONTINUE READING

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