Chongmague reveals an essential role for laminin-mediated boundary formation in chordate convergence and extension movements.

@article{Veeman2008ChongmagueRA,
  title={Chongmague reveals an essential role for laminin-mediated boundary formation in chordate convergence and extension movements.},
  author={Michael T Veeman and Yuki Nakatani and Carolyn M. Hendrickson and Vivian R. Ericson and Clarissa Lin and William C Smith},
  journal={Development},
  year={2008},
  volume={135 1},
  pages={33-41}
}
Although cell intercalation driven by non-canonical Wnt/planar cell polarity (PCP) pathway-dependent mediolateral cell polarity is important for notochord morphogenesis, it is likely that multiple mechanisms shape the notochord as it converges and extends. Here we show that the recessive short-tailed Ciona savignyi mutation chongmague (chm) has a novel defect in the formation of a morphological boundary around the developing notochord. chm notochord cells initiate intercalation normally, but… CONTINUE READING
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