Chondromucoprotein-degrading neutral protease activity in rheumatoid synovial fluid.


Erosion of articular cartilage, which is characteristic of inflammatory joint diseases, including rheumatoid arthritis (RA), is due in part to enzymic breakdown of the components of the cartilage matrix (Bollet, 1963), particularly collagen and chondromucoprotein (CMP). It has been suggested that lysozomal hydrolases, possibly derived from cells of the… (More)


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@article{Wood1971ChondromucoproteindegradingNP, title={Chondromucoprotein-degrading neutral protease activity in rheumatoid synovial fluid.}, author={G Christopher Wood and R H Pryce-Jones and Dr. David C. White and George Nuki}, journal={Annals of the rheumatic diseases}, year={1971}, volume={30 1}, pages={73-7} }