Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells treated by GSK-3 inhibitors

@article{Eslaminejad2013ChondrogenicDO,
  title={Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells treated by GSK-3 inhibitors},
  author={Mohamadreza Baghaban Eslaminejad and Negar Karimi and Maryam Shahhoseini},
  journal={Histochemistry and Cell Biology},
  year={2013},
  volume={140},
  pages={623-633}
}
A study of the cartilage differentiation of mesenchymal stem cells (MSCs) would be of particular interest since one strategy for cell-based treatment of cartilage defects emphasizes the use of cells that are in a differentiated state. The present study has attempted to evaluate the effects of two well-known glycogen synthase kinase-3 inhibitors, including lithium chloride (LiCl) and SB216763 on a human marrow-derived MSC (hMSC) chondrogenic culture. Passaged-3 MSCs were condensed into small… CONTINUE READING

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