Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix.

@article{Cheng2009ChondrogenicDO,
  title={Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix.},
  author={N M Cheng and Bradley T. Estes and Hani A Awad and Farshid Guilak},
  journal={Tissue engineering. Part A},
  year={2009},
  volume={15 2},
  pages={231-41}
}
Adipose-derived adult stem cells (ASCs) have the ability to differentiate into a chondrogenic phenotype in response to specific environmental signals such as growth factors or artificial biomaterial scaffolds. In this study, we examined the hypothesis that a porous scaffold derived exclusively from articular cartilage can induce chondrogenesis of ASCs. Human ASCs were seeded on porous scaffolds derived from adult porcine articular cartilage and cultured in standard medium without exogenous… CONTINUE READING

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