Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2.

@article{McNulty2005ChondrocyteTA,
  title={Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2.},
  author={A. McNulty and T. Vail and V. Kraus},
  journal={Biochimica et biophysica acta},
  year={2005},
  volume={1712 2},
  pages={
          212-21
        }
}
Collagen II is the major protein component of articular cartilage and forms the collagen fibril network, which provides the tensile strength of cartilage. Collagen II synthesis is enhanced by ascorbic acid (vitamin C) at both a transcriptional and post-transcriptional level. While the importance of ascorbic acid in the synthesis of collagen has been established, the mechanism by which this essential nutrient is transported into chondrocytes has not been investigated previously. We have… Expand
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