Chondrocyte deformation under extreme tissue strain in two regions of the rabbit knee joint.

@article{Madden2013ChondrocyteDU,
  title={Chondrocyte deformation under extreme tissue strain in two regions of the rabbit knee joint.},
  author={Ryan M. J. Madden and Sang-Kuy Han and Walter Herzog},
  journal={Journal of biomechanics},
  year={2013},
  volume={46 3},
  pages={554-60}
}
Articular cartilage and its native cells-chondrocytes-are exposed to a wide range of mechanical loading. Chondrocytes are responsible for maintaining the cartilage matrix, yet relatively little is known regarding their behavior under a complete range of mechanical loads or how cell mechanics are affected by region within the joint. The purpose of this study was to investigate chondrocyte deformations in situ under tissue loads ranging from physiological to extreme (0-80% nominal strain) in two… CONTINUE READING

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