Chondrocyte apoptosis increases with age in the articular cartilage of adult animals.

@article{Adams1998ChondrocyteAI,
  title={Chondrocyte apoptosis increases with age in the articular cartilage of adult animals.},
  author={Michael J. Adams and Walter Horton},
  journal={The Anatomical record},
  year={1998},
  volume={250 4},
  pages={
          418-25
        }
}
BACKGROUND Apoptosis in vivo has been identified in developing cartilage from embryonic chick sterna and avian and murine growth plates. To date, no evidence exists that chondrocytes in articular cartilage undergo apoptosis. METHODS We examined the distribution of cells demonstrating fragmented DNA in the articular knee cartilage of C57BL/6 mice (aged 11, 18, 24, and 30 months) and Wistar rats (aged 6, 12, and 24 months) using a DNA end-labeling technique. RESULTS Control experiments… CONTINUE READING
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