Cholinesterase is associated with the basal lamina at the neuromuscular junction

@article{Mcmahan1978CholinesteraseIA,
  title={Cholinesterase is associated with the basal lamina at the neuromuscular junction},
  author={U J Mcmahan and Joshua R Sanes and Lawrence M. Marshall},
  journal={Nature},
  year={1978},
  volume={271},
  pages={172-174}
}
THE cholinesterase (ChE) of skeletal muscle is concentrated at the neuromuscular junction, where it hydrolyses acetylcholine released from the nerve terminal1–5. In frog muscle treated with a histochemical stain for ChE, enzyme activity is demonstrable at all terminal branches of the neuromuscular junction (Fig. 1a), with the reaction product occupying the synaptic cleft between nerve and muscle (Fig. 1d)1,6. A particulate enzyme, ChE was assumed to be integral to the postsynaptic plasma… CONTINUE READING
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