Cholinesterase inhibitors from botanicals

  title={Cholinesterase inhibitors from botanicals},
  author={Faiyaz Ahmed and Raza Murad Ghalib and P. Sasikala and K. K. Mueen Ahmed},
  booktitle={Pharmacognosy reviews},
Alzheimer's disease (AD) is a progressive neurodegenerative disease, wherein a progressive loss of cholinergic synapses occurs in hippocampus and neocortex. Decreased concentration of the neurotransmitter, acetylcholine (ACh), appears to be critical element in the development of dementia, and the most appropriate therapeutic approach to treat AD and other form of dementia is to restore acetylcholine levels by inhibiting both major form of cholinesterase: Acetylcholinesterase (AChE) and… CONTINUE READING
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