Cholinergic urticaria. A clinical and histologic study.

  title={Cholinergic urticaria. A clinical and histologic study.},
  author={Jan V. Hirschmann and Frances M. Lawlor and John English and J B Louback and Richard K. Winkelmann and Malcolm Greaves},
  journal={Archives of dermatology},
  volume={123 4},
We studied the natural history, the prevalence of atopy, and the frequency of systemic symptoms during attacks in 35 patients with cholinergic urticaria, the histologic condition of the eruption in seven patients (20%), and the response to intradermal injections of acetylcholine, histamine, and methacholine in 18 patients (51%). In most patients symptoms began between the ages of 10 and 30 years, persisted for many years, and caused them to modify their activities to avoid the provoking factors… CONTINUE READING

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