Cholinergic systems in the rat brain: IV. descending projections of the pontomesencephalic tegmentum

  title={Cholinergic systems in the rat brain: IV. descending projections of the pontomesencephalic tegmentum},
  author={Nancy J. Woolf and Larry L. Butcher},
  journal={Brain Research Bulletin},

Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area

The concept that this cholinergic group is functionally organized in a manner which selectively innervates motor (SN) and limbic (VTA) dopaminergic nuclei is supported.

Descending brainstem projections of the pedunculopontine tegmental nucleus in the rat

SummaryDescending brainstem projections from the pedunculopontine tegmental nucleus (PPN) were studied in the rat by use of the anterograde tracerPhaseolus vulgaris-leucoagglutinin (PHA-L) and the

Serotonergic dorsal raphe nucleus projections to the cholinergic and noncholinergic neurons of the pedunculopontine tegmental region: a light and electron microscopic anterograde tracing and immunohistochemical study

This serotonergic dorsal raphe innervation may modulate cholinergic PPT neurons during alterations in behavioral state and the role of these projections in the initiation of rapid eye movement (REM) sleep and the ponto‐geniculo‐occipital waves that precede and accompany REM sleep is discussed.

Distribution of choline acetyltransferase immunoreactive axons and terminals in the rat and ferret brainstem

The distribution of staining for AChE activity reflected that of the distribution of ChAT immunoreactivity in the brainstem, except in a few regions where there were also species differences in the distributionof ChAT‐positive terminals, e.g., in the superficial grey layer of the superior colliculus and in the substantia nigra.



Brainstem afferents to the magnocellular basal forebrain studied by axonal transport, immunohistochemistry, and electrophysiology in the rat

Brainstem afferents to the magnocellular basal forebrain were studied by using tract tracing, immunohistochemistry and extracellular recordings in the rat to find labelled neurons in the substantia nigra pars compacta, mesencephalic and pontine reticular formation.

The afferent and efferent connections of the feline nucleus tegmenti pedunculopontinus, pars compacta

In the cat, TPc can most readily be identified by the terminal distribution of fibers originating in the substantia nigra, and the limits of TPc were estimated on the basis of autoradiographic experiments.