Cholinergic systems in the rat brain: IV. descending projections of the pontomesencephalic tegmentum

@article{Woolf1989CholinergicSI,
  title={Cholinergic systems in the rat brain: IV. descending projections of the pontomesencephalic tegmentum},
  author={Nancy J. Woolf and Larry L. Butcher},
  journal={Brain Research Bulletin},
  year={1989},
  volume={23},
  pages={519-540}
}
Descending projections from cholinergic neurons in the pedunculopontine and laterodorsal tegmental nuclei, collectively referred to as the pontomesencephalotegmental (PMT) cholinergic complex, were studied by use of the fluorescent retrograde tracers fluorogold, true blue, or Evans Blue in combination with choline acetyltransferase (ChAT) immunohistochemistry of acetylcholinesterase (AChE) pharmacohistochemistry. Pedunculopontine somata positive for ChAT or staining intensely for AChE were… Expand
Characterization of the extent of pontomesencephalic cholinergic neurons' projections to the thalamus: comparison with projections to midbrain dopaminergic groups
TLDR
Findings indicate that the diverse physiological and behavioral effects attributed to the activity of pontomesencephalic cholinergic neurons should not be dissociated from their activating effects in the thalamus. Expand
Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area
TLDR
The concept that this cholinergic group is functionally organized in a manner which selectively innervates motor (SN) and limbic (VTA) dopaminergic nuclei is supported. Expand
Single cholinergic mesopontine tegmental neurons project to both the pontine reticular formation and the thalamus in the rat
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Organization of choline acetyltransferase-containing structures in the cranial nerve motor nuclei and spinal cord of the monkey
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Observed structures in the cranial nerve motor nuclei and ventral and lateral horns of the spinal cord of the monkey suggest that the organization of the motoruclei is complex, at least regarding the cholinoceptivity. Expand
Serotonergic dorsal raphe nucleus projections to the cholinergic and noncholinergic neurons of the pedunculopontine tegmental region: a light and electron microscopic anterograde tracing and immunohistochemical study
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Cholinergic cells in the tegmentum send branching projections to the inferior colliculus and the medial geniculate body
TLDR
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TLDR
The distribution of staining for AChE activity reflected that of the distribution of ChAT immunoreactivity in the brainstem, except in a few regions where there were also species differences in the distributionof ChAT‐positive terminals, e.g., in the superficial grey layer of the superior colliculus and in the substantia nigra. Expand
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The ascending cholinergic projections of the pedunculopontine and dorsolateral tegmental nuclei, referred to collectively as the pontomesencephalotegmental (PMT) cholinergic complex, wereExpand
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TLDR
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