Cholinergic reversal of isoflurane anesthesia in rats as measured by cross-approximate entropy of the electroencephalogram.

@article{Hudetz2003CholinergicRO,
  title={Cholinergic reversal of isoflurane anesthesia in rats as measured by cross-approximate entropy of the electroencephalogram.},
  author={Anthony G. Hudetz and Jamie Wood and John Paul Kampine},
  journal={Anesthesiology},
  year={2003},
  volume={99 5},
  pages={
          1125-31
        }
}
BACKGROUND Pharmacologic modulation of the state of consciousness is of interest for clinical practice and for a better understanding of anesthetic mechanisms. The cholinergic activating system is an important regulator of the state of consciousness during general anesthesia. Entropy of the electroencephalogram has been proposed as a promising measure of anesthetic depth. The authors have shown that volatile anesthetics decrease cross-approximate entropy (C-ApEn) of the bihemispheric frontal… CONTINUE READING
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