Cholinergic regulation of fear learning and extinction.

  title={Cholinergic regulation of fear learning and extinction.},
  author={Marlene A. Wilson and Jim R Fadel},
  journal={Journal of neuroscience research},
  volume={95 3},
Cholinergic activation regulates cognitive function, particularly long-term memory consolidation. This Review presents an overview of the anatomical, neurochemical, and pharmacological evidence supporting the cholinergic regulation of Pavlovian contextual and cue-conditioned fear learning and extinction. Basal forebrain cholinergic neurons provide inputs to neocortical regions and subcortical limbic structures such as the hippocampus and amygdala. Pharmacological manipulations of muscarinic and… CONTINUE READING
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