Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development: implications for hypoxia tolerance and perinatal mortality.

@article{Slotkin1999CholinergicRI,
  title={Cholinergic receptors in heart and brainstem of rats exposed to nicotine during development: implications for hypoxia tolerance and perinatal mortality.},
  author={Theodore A. Slotkin and Timothy Epps and M L Stenger and Keith Sawyer and Frederic J. Seidler},
  journal={Brain research. Developmental brain research},
  year={1999},
  volume={113 1-2},
  pages={1-12}
}
Cigarette smoking during pregnancy increases the incidence of perinatal mortality and Sudden Infant Death Syndrome (SIDS). We have evaluated prenatal or postnatal nicotine exposure in developing rats to examine the potential role of altered neurotransmitter receptor expression in these processes. Pregnant rats received continuous infusions of nicotine throughout gestation, at doses mimicking the plasma levels found in smokers. After birth, cardiac M2-muscarinic cholinergic receptors, which are… CONTINUE READING

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Prenatal Exposure to Snus Alters Heart Rate Variability in the Infant.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco • 2017

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