Cholinergic receptor subtypes in the olfactory bulbectomy model of depression

@article{Slotkin2006CholinergicRS,
  title={Cholinergic receptor subtypes in the olfactory bulbectomy model of depression},
  author={Theodore A. Slotkin and Frederic J. Seidler},
  journal={Brain Research Bulletin},
  year={2006},
  volume={68},
  pages={341-345}
}
The connection between smoking and depression, the antidepressant actions of nicotine and the targeting of nicotinic acetylcholine receptors (nAChRs) by monoamine re-uptake inhibitors all point to a potential role of nAChRs in the etiology and/or symptomatology of depression. In the current study, we evaluated nAChR subtypes in brain regions of rats subjected to olfactory bulbectomy (OBX), a standard animal model that recapitulates many of the behavioral and neurochemical alterations thought to… CONTINUE READING
BETA

Similar Papers

Loading similar papers…