Cholinergic neurochemical development of normal and deafferented antennal lobes during metamorphosis of the moth, Manduca sexta.

@article{Sanes1977CholinergicND,
  title={Cholinergic neurochemical development of normal and deafferented antennal lobes during metamorphosis of the moth, Manduca sexta.},
  author={Joshua R Sanes and David J. Prescott and John G. Hildebrand},
  journal={Brain research},
  year={1977},
  volume={119 2},
  pages={389-402}
}
Sensory neurons with somata in the antennae of the moth, Manduca sexta, make synapses in the antennal lobes of the brain. These lobes develop during metamorphosis of the pupa to the adult while the antennae themselves develop and send presumably cholinergic sensory fibers into the lobes. Levels of acetylcholine, choline acetyltransferase, and acetylcholinesterase rise dramatically in the lobes as sensory axons grow from the antennae to the lobes through the antennal nerves. An [125I]alpha… CONTINUE READING

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