Cholinergic modulation of preattentive auditory processing in aging.

@article{Pekkonen2005CholinergicMO,
  title={Cholinergic modulation of preattentive auditory processing in aging.},
  author={Eero Pekkonen and Iiro P. J{\"a}{\"a}skel{\"a}inen and Seppo Kaakkola and Jyrki Ahveninen},
  journal={NeuroImage},
  year={2005},
  volume={27 2},
  pages={387-92}
}
Auditory event-related potential (ERP) components P50 and N100 are thought to index preattentive auditory processing underlying stimulus detection, whereas a subsequent component termed mismatch negativity (MMN) has been proposed to reflect comparison of incoming stimuli to a short-lived sensory memory trace of preceding sounds. Existing evidence suggests impairment of preattentive auditory processing in aging, which appears to be accompanied by decline of cholinergic activity. Previous studies… CONTINUE READING

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