Cholinergic modulation of anaphylactic shock: plasma proteins influence.

@article{Nezhinskaya2007CholinergicMO,
  title={Cholinergic modulation of anaphylactic shock: plasma proteins influence.},
  author={G. I. Nezhinskaya and A. L. Vladykin and N. Sapronov},
  journal={Life sciences},
  year={2007},
  volume={80 24-25},
  pages={
          2342-6
        }
}
Cholinergic drugs can modulate anaphylactic shock and change lymphocyte functions. Plasma proteins modulate effects of muscarinic antagonists during anaphylactic shock. The present investigation was carried out to study the antianaphylactic activity of methacine (antagonist at muscarinic receptors) in combination with neostigmine (anticholinesterase drug). However, it is not known whether plasma proteins-albumin, C-reactive protein (CRP) and immunoglobulin G (IgG) - modify the effects of… Expand

References

SHOWING 1-10 OF 15 REFERENCES
Anaphylactic shock: mechanisms and treatment.
This paper reviews the mechanisms of anaphylactic shock in terms of the immunoglobulin and non-immunoglobulin triggering events, and the cellular events based on the rise in intracellular cyclic AMPExpand
Anaphylaxis During the Perioperative Period
TLDR
Anaphylactic reactions occur on reexposure to a specific antigen and requires the release of proinflammatory mediators through a direct non-immunoglobulin E-mediated release of mediators from mast cells or from complement activation. Expand
The lymphocytic cholinergic system and its contribution to the regulation of immune activity.
TLDR
The facts that lymphocytic cholinergic activity reflects well the changes in immune system function seen in animal models of immune deficiency and immune acceleration provide a compelling picture in which lymphocytes constitute a Cholinergic system that is independent of cholin allergic nerves, and which is involved in the regulation of immune function. Expand
Interleukin-1 increases splenic blood flow by affecting the sympathetic vasoconstrictor tonus.
TLDR
The results show that a cytokine released by activated immune cells can regulate the blood flow of a main lymphoid organ, the spleen, by affecting mechanisms under neural control. Expand
Blockage of Mouse Muscle Nicotinic Receptors by Serotonergic Compounds
TLDR
It is concluded that 5‐HT and serotonergic agents inhibit, in a non‐competitive manner, the ACh‐current in muscle AChRs by blocking the open receptor‐channel complex. Expand
Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands.
TLDR
The sensitizing actions of galanthamine, 5-hydroxytryptamine, and related compounds, at submicromolar concentrations, may reflect the existence of cross-talk between adjacent neuroreceptors and synapses in the central nervous system and thus suggests the formation of transiently active chemical networks in the vertebrate brain. Expand
IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking.
TLDR
It is demonstrated that IgG Ab produced during the course of an immune response or administered passively can completely suppress IgE-mediated anaphylaxis and that both allergen interception and Fc gammaRIIb-dependent inhibition contribute to in vivo blocking Ab activity. Expand
Serotonin upregulates mitogen-stimulated B lymphocyte proliferation through 5-HT1A receptors.
TLDR
Results show that serotonin upregulates mitogen-stimulated B lymphocyte proliferation through 5-HT1A receptors, thus providing an important link between this neurotransmitter and the immune system. Expand
Interleukin 6 and C-reactive protein levels in patients with acute allergic reactions: an emergency department-based study.
  • R. Lin, M. R. Trivino, +6 authors R. Westfal
  • Medicine
  • Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • 2001
TLDR
CRP and IL-6 levels are not simple surrogate markers for histamine or tryptase release by mast cells or basophils in acute allergic reactions and are speculated to characterize a late-phase response in immediate hypersensitivity reactions. Expand
Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines
TLDR
Results indicate that both neuronal-type Nc and Ms ACh receptors are present on the surface of lymphocytes, to investigate whether ACh in the blood acts on lymphocytes and participates in the modulation of immune responses. Expand
...
1
2
...