Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.

@article{Hong2013CholinergicLA,
  title={Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.},
  author={Elim Hong and K. Santhakumar and Courtney A Akitake and Sang Jung Ahn and Christine I Thisse and Bernard V Thisse and Claire Wyart and Jean-Marie Mangin and Marnie E Halpern},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 52},
  pages={21171-6}
}
The habenulo-interpeduncular pathway, a highly conserved cholinergic system, has emerged as a valuable model to study left-right asymmetry in the brain. In larval zebrafish, the bilaterally paired dorsal habenular nuclei (dHb) exhibit prominent left-right differences in their organization, gene expression, and connectivity, but their cholinergic nature was unclear. Through the discovery of a duplicated cholinergic gene locus, we now show that choline acetyltransferase and vesicular… CONTINUE READING
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