Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.

  title={Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway.},
  author={Elim Hong and K. Santhakumar and Courtney A Akitake and Sang Jung Ahn and Christine I Thisse and Bernard V Thisse and Claire Wyart and Jean-Marie Mangin and Marnie E Halpern},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={110 52},
The habenulo-interpeduncular pathway, a highly conserved cholinergic system, has emerged as a valuable model to study left-right asymmetry in the brain. In larval zebrafish, the bilaterally paired dorsal habenular nuclei (dHb) exhibit prominent left-right differences in their organization, gene expression, and connectivity, but their cholinergic nature was unclear. Through the discovery of a duplicated cholinergic gene locus, we now show that choline acetyltransferase and vesicular… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 6 times over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 18 extracted citations


Publications referenced by this paper.
Showing 1-10 of 77 references

Cloning and expression of tachykinins and their association with kisspeptins in the brains of zebrafish

  • S Ogawa
  • J Comp Neurol 520(13):2991–3012
  • 2012

Organization of the cholinergic systems in the brain of two lung fi shes , Protopterus dolloi and Neo - ceratodus forsteri

  • L Villani, S Battistini, R Bissoli, A Contestabile
  • Brain Struct Funct
  • 2012

Similar Papers

Loading similar papers…