Cholinergic innervation of the frontal cortex: differences among humans, chimpanzees, and macaque monkeys.

@article{Raghanti2008CholinergicIO,
  title={Cholinergic innervation of the frontal cortex: differences among humans, chimpanzees, and macaque monkeys.},
  author={Mary Ann Raghanti and Cheryl D. Stimpson and Jennifer L. Marcinkiewicz and Joseph M. Erwin and Patrick R. Hof and Chet C. Sherwood},
  journal={The Journal of comparative neurology},
  year={2008},
  volume={506 3},
  pages={409-24}
}
Cholinergic innervation of the frontal cortex is important in higher cognitive functions and may have been altered in humans relative to other species to support human-specific intellectual capacities. To evaluate this hypothesis we conducted quantitative comparative analyses of choline acetyltransferase-immunoreactive axons in cortical areas 9, 32, and 4 among humans, chimpanzees, and macaque monkeys. Area 9 of the dorsolateral prefrontal cortex is involved in inductive reasoning and specific… CONTINUE READING
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