Cholinergic innervation and muscarinic receptors in the human prostate.

  title={Cholinergic innervation and muscarinic receptors in the human prostate.},
  author={Lambertus P Witte and Christopher R Chapple and Jean J. M. C. H. de la Rosette and Martin C Michel},
  journal={European urology},
  volume={54 2},
OBJECTIVE In light of recent interest in the use of muscarinic receptor antagonists for the treatment of male lower urinary tract symptoms, understanding how such drugs work not only on the bladder but also on the prostate is important. METHODS A literature review was conducted to identify studies on the cholinergic innervation and presence and function of muscarinic acetylcholine receptors in the human prostate. RESULTS The available studies demonstrate a dense cholinergic innervation… CONTINUE READING
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