Cholinergic excitation of septohippocampal GABA but not cholinergic neurons: implications for learning and memory.

@article{Wu2000CholinergicEO,
  title={Cholinergic excitation of septohippocampal GABA but not cholinergic neurons: implications for learning and memory.},
  author={Min Wu and Marya Shanabrough and Csaba L{\'e}r{\'a}nth and Meenakshi Alreja},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2000},
  volume={20 10},
  pages={3900-8}
}
The medial septum/diagonal band (MSDB), which gives rise to the septohippocampal pathway, is a critical locus for the mnemonic effects of muscarinic drugs. Infusion of muscarinic cholinergic agonists into the MSDB enhance learning and memory processes both in young and aged rats and produce a continuous theta rhythm in the hippocampus. Intraseptal muscarinic agonists also alleviate the amnesic syndrome produced by systemic administration of muscarinic receptor antagonists. It has been presumed… CONTINUE READING
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