Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release.

  title={Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release.},
  author={Lifen Zhang and Fu-Ming Zhou and John A Dani},
  journal={Molecular pharmacology},
  volume={66 3},
Alzheimer's disease is a neurodegenerative disorder associated with a decline in cognitive abilities. Patients also frequently have noncognitive symptoms, such as anxiety, depression, apathy, and psychosis, that impair daily living. The most commonly prescribed treatments for Alzheimer's disease are acetylcholinesterase inhibitors, such as donepezil and galantamine. Enhanced cholinergic functions caused by these compounds are believed to underlie improvements in learning, memory, and attention… CONTINUE READING
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