Cholinergic activation of medial pontine reticular formation neurons in vitro.

@article{Greene1989CholinergicAO,
  title={Cholinergic activation of medial pontine reticular formation neurons in vitro.},
  author={Robert W Greene and Helmut L. Haas and Urs Gerber and R. W. McCarley},
  journal={EXS},
  year={1989},
  volume={57},
  pages={123-37}
}
In vivo microinjections of cholinergic compounds into the medial pontine reticular formation have produced some or depending on the injection site, all of the phenomena of REM, thus providing the only adequate pharmacological model of this behavioral state. The necessary anatomical substrate, a cholinergic projection to the mPRF was recently demonstrated, however the direct effect of cholinergic agonists on mPRF neurons is unknown. We have examined the effects of carbachol on mPRF neurons… CONTINUE READING
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