Choline transporters in human lung adenocarcinoma: expression and functional implications.

@article{Wang2007CholineTI,
  title={Choline transporters in human lung adenocarcinoma: expression and functional implications.},
  author={Tao Wang and Jinjun Li and Fei Chen and Yingjun Zhao and Xianghuo He and D. K. S. Wan and Jianren Gu},
  journal={Acta biochimica et biophysica Sinica},
  year={2007},
  volume={39 9},
  pages={
          668-74
        }
}
Choline is an essential nutrient for cell survival and proliferation, however, the expression and function of choline transporters have not been well identified in cancer. In this study, we detected the mRNA and protein expression of organic cation transporter OCT3, carnitine/cation transporters OCTN1 and OCTN2, and choline transporter-like protein CTL1 in human lung adenocarcinoma cell lines A549, H1299 and SPC-A-1. Their expression pattern was further confirmed in 25 human primary… CONTINUE READING
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