Choline transport in human placental brush-border membrane vesicles.

@article{Grassl1994CholineTI,
  title={Choline transport in human placental brush-border membrane vesicles.},
  author={Steven M Grassl},
  journal={Biochimica et biophysica acta},
  year={1994},
  volume={1194 1},
  pages={203-13}
}
Pathways for transport of choline by human placental epithelia were investigated using brush border membrane vesicles isolated by divalent cation precipitation. The presence of choline transport mechanisms mediating Na(+)-choline cotransport, choline/H+ exchange and facilitated diffusion were assessed from [3H]choline tracer flux measurements. The rate and magnitude of intravesicular choline accumulation was unaffected by the imposition of an inwardly directed Na+ gradient suggesting an absence… CONTINUE READING
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