Choline rise in the rat hippocampus induced by electroconvulsive shock treatment.

@article{Sartorius2003CholineRI,
  title={Choline rise in the rat hippocampus induced by electroconvulsive shock treatment.},
  author={Alexander Sartorius and Claudia Neumann-Haefelin and Barbara Vollmayr and Mathias Hoehn and Fritz A. Henn},
  journal={Biological psychiatry},
  year={2003},
  volume={53 7},
  pages={620-3}
}
BACKGROUND Human hippocampal choline decreases in major depression episodes. This decrease was recently measured by 1H magnetic resonance spectroscopy (MRS), and it has been found that its level normalizes during antidepressive electroconvulsive therapy. We hypothesized a hippocampal choline increase in the rat brain under electroconvulsive shock (ECS) treatment. METHODS Rat hippocampi (n = 28) were investigated via magnetic resonance spectroscopy and signal intensities of choline (Cho… CONTINUE READING