Choline phosphate functionalized surface: protein-resistant but cell-adhesive zwitterionic surface potential for tissue engineering.

Abstract

A choline phosphate (CP) modified surface is designed to resist protein adsorption due to its zwitterionic properties and simultaneously promote cell adhesion though its universal interaction with phosphate choline (PC) headgroups of the cell membrane. This work provides a new approach to obtain a cell-adhesive surface with a non-biofouling 'background', which has a potential for tissue engineering.

DOI: 10.1039/c4cc08681c

Cite this paper

@article{Chen2015CholinePF, title={Choline phosphate functionalized surface: protein-resistant but cell-adhesive zwitterionic surface potential for tissue engineering.}, author={Xingyu Chen and Tianchan Chen and Zaifu Lin and Xian'e Li and Wei Wu and Jianshu Li}, journal={Chemical communications}, year={2015}, volume={51 3}, pages={487-90} }