Choline: critical role during fetal development and dietary requirements in adults.

  title={Choline: critical role during fetal development and dietary requirements in adults.},
  author={S. Zeisel},
  journal={Annual review of nutrition},
  • S. Zeisel
  • Published 2006
  • Biology, Medicine
  • Annual review of nutrition
  • Choline is an essential nutrient needed for the structural integrity and signaling functions of cell membranes; for normal cholinergic neurotransmission; for normal muscle function; for lipid transport from liver; and it is the major source of methyl groups in the diet. Choline is critical during fetal development, when it influences stem cell proliferation and apoptosis, thereby altering brain and spinal cord structure and function and influencing risk for neural tube defects and lifelong… CONTINUE READING
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