Choline, an essential nutrient for humans.

@article{Zeisel1991CholineAE,
  title={Choline, an essential nutrient for humans.},
  author={Steven H Zeisel and Kerry Ann da Costa and Patricia D. Franklin and Emily A Alexander and John Thomas Lamont and Nancy F. Sheard and Alexa L Beiser},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={1991},
  volume={5 7},
  pages={
          2093-8
        }
}
Choline is required to make essential membrane phospholipids. It is a precursor for the biosynthesis of the neurotransmitter acetylcholine and also is an important source of labile methyl groups. Mammals fed a choline-deficient diet develop liver dysfunction; however, choline is not considered an essential nutrient in humans. Healthy male volunteers were hospitalized and fed a semisynthetic diet devoid of choline supplemented with 500 mg/day choline for 1 wk. Subjects were randomly divided into… CONTINUE READING
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Vitamin-like” molecules: choline

  • S. H. Zeisel
  • In Modern Nutrition in Health and Disease(Shils,
  • 1988
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